American scientists at the University of California have offered a new approach to the age of the brain and the fight against Alzheimer's disease. It turned out that the combination of Nicotinamid (a form of vitamin B3) and green tea contributes to the restoration of the level of energy molecule in neurons and improves the cell "cleaning" process, which cleanses the cells from poisonous proteins. The work was published in the GEROSCIENCE magazine.
The main study of the study was Guanozin Triphosphate (GTP) molecule responsible for transporting and processing damaged proteins. Scientists have found that GTP reserves are declining with age, especially in brain cells with signs of Alzheimer's disease. This leads to the accumulation of troubleshooters and dangerous protein units.
The treatment of old neurons with a mixture of Nicotinamide and EGCG has recovered the GTP level of almost "young" values, activated by Rab7 and Arl8b for removal of mobile "garbage", and reduced the accumulation of amyloids, which is the main pathological protein of Alzheimer's disease. In addition, protein's oxidative damage has been declining and increasing the survival of cells.
"I was surprised how effective the nicotinamide and EGCG combination reduced the level of oxidized proteins and cleared the cells from amyloid," said Professor Gregory J. Brunder.
However, the authors emphasize that in order to confirm the results, large-scale research on animals and people is needed. In addition, these materials contained in their usual forms are rapidly decomposed into the body, so scientists must find ways to bring the compounds immediately to brain.
Translation of: Euromedia24.com
