Alcohol dependence often begins as a pleasure search, but over time it turns into an attempt to avoid painful withdrawal symptoms. The new study of scientists at the Scrip Institute has shown that a small part of the brain, the dalamus's parentrrric core (PVT) plays an important role in this process. The study was published "Biological Psychiatry. Global Open Science "(BP) magazine.
"The difficulty of overcoming the dependence is not only the aspiration of pleasure, but also the desire to avoid intensive stress and anxiety during the withdrawal. We found out which systems of the brain are particularly registering this training, and why it makes it so stable, "said Friedbert Weiss, a professor in the study.
Scientists have experimented with rats. Animals, initially conditioned by alcohol, learned to connect a certain environment and action (lever compression) with alcohol relief. Later, when alcohol was removed, the conditions for the experience were a strong and compulsive wish for another dose.
When researchers studied the rats' brain, they noticed that the millimus's parentrrrrric nuclei was sharply activated in this group. This pattern has not been observed in other animals, depending on animals that did not have the ability to learn withdrawal, or those who drank for pleasure.
"This passage is literally illuminated with all the animals who had to teach withdrawal," said Hermina Nedelescu, co-authored. "This reveals the nervous chains that make contact between alcohol and stress relief."
Scientists believe that the millimus's parentrrrric core works as a "knot" system to develop emotionally significant information. Its activity can be the basis for the so-called hedonic aloshazase, in which case the brain awarding system is chronically unbalanced, which leads to the fact that a person constantly feels a negative background and is looking for relief.
Translation of: Euromedia24.com
