Scientists from Nanjing Chinese University of Chinese Medicine have found that the vitamin P) is slowing down (vitamin P) slows the progress of the liver fibrosis. The results of the study were published in the Biomolecules and Biomedicine magazine.
Liver Fibrosis is a pathology caused by chronic diseases such as viral hepatitis, alcoholic liver disease and non-alcoholic fat liver disease (NAFLD). Without treatment, fibrosis can lead to cirrhosis, liver cancer and liver deficiency.
To date, the treatment of fibrosis is mainly supported. There are no drugs that directly affect the fibrous process.
The promising field of treatment is the targeting of Glycolysis, the process that cells produce energy. In particular, scientists are studying the influence of Glycolysis in the liver synusoid endotelle cells (LSEC) that forms blood vessels. If they don't work correctly, they can lead to inflammation and fibrosis.
Studies on mice have shown that natural flavonoids will be able to slow down the progress of the liver fibrosis, influencing Glycolysis. Will be taken to reduce the activity of the main enzymes involved in this process. In addition, it will be able to prevent fibrosis, reducing the level of CXCL1, a molecular, which attracts neutrophiles (immune cells) to places of inflammation.
In the tests of mice, the voting has shown good results in reducing the levels of liver enzymes and fibrosis (hyaluronic acid and prolocum III). It also reduces collagen accumulation in the liver that helps prevent tissue condensation.
Scientists have said that further research is needed to establish those influences. If they are successful, the voter can become a new way of treating the liver disease, expanding therapeutic options beyond the relief of symptoms.
Translation of: Euromedia24.com
